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Selection of self-reactive T cells in the thymus
On the whole, the healthy adaptive immune system is responsive to foreign antigens, and tolerant to self. However many individual lymphocytes have, and even require, substantial self-reactivity for their particular functions in immunity. In this review, we discuss several populations of lymphocytes...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518413/ https://ncbi.nlm.nih.gov/pubmed/22149933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-020711-075035 |
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