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Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling
Positive selection occurs in the thymic cortex, but critical maturation events occur later in the medulla. We defined the precise stage at which T cells acquire competence to proliferate and emigrate. Transcriptome analysis of late gene changes suggested roles for NF-κB and interferon (IFN) signalin...
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| Publicado no: | Nat Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837029/ https://ncbi.nlm.nih.gov/pubmed/27043411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3419 |
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