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Post-selection thymocyte maturation and emigration are independent of IL-7 and ERK5
The transcription factor Kruppel-Like Factor 2 (KLF2) controls the emigration of conventional T cells from the thymus through its regulation of the cell surface receptor, S1P1. Prior to KLF2 expression, developing T cells require a positive selection signal through the T cell receptor. However, foll...
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| 出版年: | J Immunol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980999/ https://ncbi.nlm.nih.gov/pubmed/21187442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002238 |
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