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Classical MHC expression by DP thymocytes impairs the selection of non-classical MHC restricted innate-like T cells
Conventional T cells are selected by peptide-MHC expressed by cortical epithelial cells in the thymus, and not by cortical thymocytes themselves that do not express MHC I or MHC II. Instead, cortical thymocytes express non-peptide presenting MHC molecules like CD1d and MR1, and promote the selection...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8052364/ https://ncbi.nlm.nih.gov/pubmed/33863906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22589-z |
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