From pre-DP, post-DP, SP4, and SP8 Thymocyte Cell Counts to a Dynamical Model of Cortical and Medullary Selection

Cells of the mature αβ T cell repertoire arise from the development in the thymus of bone marrow precursors (thymocytes). αβ T cell maturation is characterized by the expression of thousands of copies of identical αβ T cell receptors and the CD4 and/or CD8 co-receptors on the surface of thymocytes....

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Hlavní autoři: Sawicka, Maria, Stritesky, Gretta L., Reynolds, Joseph, Abourashchi, Niloufar, Lythe, Grant, Molina-París, Carmen, Hogquist, Kristin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924582/
https://ncbi.nlm.nih.gov/pubmed/24592261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00019
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