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Mathematical Model of Naive T Cell Division and Survival IL-7 Thresholds

We develop a mathematical model of the peripheral naive T cell population to study the change in human naive T cell numbers from birth to adulthood, incorporating thymic output and the availability of interleukin-7 (IL-7). The model is formulated as three ordinary differential equations: two describ...

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Main Authors: Reynolds, Joseph, Coles, Mark, Lythe, Grant, Molina-París, Carmen
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870322/
https://ncbi.nlm.nih.gov/pubmed/24391638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00434
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