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Post-selection thymocyte maturation and emigration are independent of IL-7 and ERK5

The transcription factor Kruppel-Like Factor 2 (KLF2) controls the emigration of conventional T cells from the thymus through its regulation of the cell surface receptor, S1P1. Prior to KLF2 expression, developing T cells require a positive selection signal through the T cell receptor. However, foll...

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Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Weinreich, Michael A., Jameson, Stephen C., Hogquist, Kristin A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980999/
https://ncbi.nlm.nih.gov/pubmed/21187442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002238
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