Φορτώνει......

The self-obsession of T cells: how TCR signaling thresholds affect fate decisions in the thymus and effector function in the periphery

Self-reactivity was once seen as a potential characteristic of T cells that was eliminated by clonal selection to protect the host from autoimmune pathology. We now appreciate that the T cell repertoire is in fact, broadly self-reactive, one could even say self-centered. The strength with which a T...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nat Immunol
Κύριοι συγγραφείς: Hogquist, Kristin A., Jameson, Stephen C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348363/
https://ncbi.nlm.nih.gov/pubmed/25137456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2938
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!