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Selection of self-reactive T cells in the thymus

On the whole, the healthy adaptive immune system is responsive to foreign antigens, and tolerant to self. However many individual lymphocytes have, and even require, substantial self-reactivity for their particular functions in immunity. In this review, we discuss several populations of lymphocytes...

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Sonraí Bibleagrafaíochta
Main Authors: Stritesky, Gretta L., Jameson, Stephen C., Hogquist, Kristin A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518413/
https://ncbi.nlm.nih.gov/pubmed/22149933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-020711-075035
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