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Murine thymic selection quantified using a unique method to capture deleted T cells
Thymic positive and negative selection events generate a T-cell repertoire that is MHC restricted and self-tolerant. The number of T cells undergoing positive and negative selection in normal mice has never been firmly established. We generated mice that lack the proapoptotic molecule Bim (bcl2l11)...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606987/ https://ncbi.nlm.nih.gov/pubmed/23487759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217532110 |
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