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Specificity and flexibility in thymic selection

During positive selection, developing thymocytes are rescued from programmed cell death by T-cell receptor (TCR)-mediated recognition of major histocompatibility complex (MHC) molecules1–3. MHC-bound peptides contribute to this process4–8. Recently we identified individual MHC-binding peptides which...

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Detalhes bibliográficos
Main Authors: Jameson, Stephen C., Hogquist, Kristin A., Bevan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778728/
https://ncbi.nlm.nih.gov/pubmed/8008067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/369750a0
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