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Thymoproteasome subunit-β5T generates peptide-MHC complexes specialized for positive selection
Cortical thymic epithelial cells (cTECs) express a unique thymoproteasome subunit-β5T that plays an essential role in the development of CD8 T cells. In contrast, the immunoproteasome subunit-β5i is expressed in other thymic antigen-presenting cells (APCs). The thymoproteasome may generate peptides...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637736/ https://ncbi.nlm.nih.gov/pubmed/23569244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222244110 |
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