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The TCR’s sensitivity to self-peptide–MHC dictates the ability of naïve CD8(+) T cells to respond to foreign antigens
The strength of self-peptide–major histocompatibility complex (MHC) recognition dictates naïve CD8(+) T cell homeostasis, but its effect on foreign antigen reactivity is controversial. As CD5 expression correlates with self-recognition, we studied CD5(lo) and CD5(hi) naïve CD8(+) T cells. Gene expre...
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| Pubblicato in: | Nat Immunol |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270846/ https://ncbi.nlm.nih.gov/pubmed/25419629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3043 |
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