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Thymoproteasomes produce unique peptide motifs for positive selection of CD8(+) T cells
Positive selection in the thymus provides low-affinity T-cell receptor (TCR) engagement to support the development of potentially useful self-major histocompatibility complex class I (MHC-I)-restricted T cells. Optimal positive selection of CD8(+) T cells requires cortical thymic epithelial cells th...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4557289/ https://ncbi.nlm.nih.gov/pubmed/26099460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8484 |
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