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Krüppel-like factor 2 (KLF2) regulates B-cell reactivity, subset differentiation, and trafficking molecule expression

The transcription factor Krüppel-like factor 2 (KLF2) is critical for normal trafficking of T lymphocytes, but its role in B cells is unclear. We report that B cell-specific KLF2 deficiency leads to decreased expression of the trafficking molecules CD62L and β7-integrin, yet expression of sphingosin...

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Bibliografiske detaljer
Main Authors: Hart, Geoffrey T., Wang, Xiaodan, Hogquist, Kristin A., Jameson, Stephen C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021025/
https://ncbi.nlm.nih.gov/pubmed/21187410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013168108
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