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Krüppel-like factor 2 (KLF2) is required for phenotypic maintenance but not development of B1 B cells

Several recent studies reported that Krüppel-like factor 2 (KLF2) controls trafficking, development, and function of B cells. Conditional B cell KLF2 knockout mice have increased numbers of MZ B cells and decreased numbers of B1 phenoytpe cells. However, it was unclear whether KLF2 is required for B...

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Autori principali: Hart, Geoffrey T., Peery, Stephen L., Hamilton, Sara E., Jameson, Stephen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448866/
https://ncbi.nlm.nih.gov/pubmed/22942434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201439
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