Krüppel-Like Factor 2 Is Required for Normal Mouse Cardiac Development

Krüppel-like factor 2 (KLF2) is expressed in endothelial cells in the developing heart, particularly in areas of high shear stress, such as the atrioventricular (AV) canal. KLF2 ablation leads to myocardial thinning, high output cardiac failure and death by mouse embryonic day 14.5 (E14.5) in a mixe...

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Detalhes bibliográficos
Main Authors: Chiplunkar, Aditi R., Lung, Tina K., Alhashem, Yousef, Koppenhaver, Benjamin A., Salloum, Fadi N., Kukreja, Rakesh C., Haar, Jack L., Lloyd, Joyce A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573061/
https://ncbi.nlm.nih.gov/pubmed/23457456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054891
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