Krüppel-Like Factor 2 Is Required for Normal Mouse Cardiac Development

Krüppel-like factor 2 (KLF2) is expressed in endothelial cells in the developing heart, particularly in areas of high shear stress, such as the atrioventricular (AV) canal. KLF2 ablation leads to myocardial thinning, high output cardiac failure and death by mouse embryonic day 14.5 (E14.5) in a mixe...

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Bibliografiske detaljer
Main Authors: Chiplunkar, Aditi R., Lung, Tina K., Alhashem, Yousef, Koppenhaver, Benjamin A., Salloum, Fadi N., Kukreja, Rakesh C., Haar, Jack L., Lloyd, Joyce A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573061/
https://ncbi.nlm.nih.gov/pubmed/23457456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054891
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