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Elimination of Self-Reactive T Cells in the Thymus: A Timeline for Negative Selection

The elimination of autoreactive T cells occurs via thymocyte apoptosis and removal by thymic phagocytes, but the sequence of events in vivo, and the relationship between thymocyte death and phagocytic clearance, are unknown. Here we address these questions by following a synchronized cohort of thymo...

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Détails bibliographiques
Auteurs principaux: Dzhagalov, Ivan Lilyanov, Chen, Katherine Grace, Herzmark, Paul, Robey, Ellen A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660248/
https://ncbi.nlm.nih.gov/pubmed/23700386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001566
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