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Elimination of Self-Reactive T Cells in the Thymus: A Timeline for Negative Selection

The elimination of autoreactive T cells occurs via thymocyte apoptosis and removal by thymic phagocytes, but the sequence of events in vivo, and the relationship between thymocyte death and phagocytic clearance, are unknown. Here we address these questions by following a synchronized cohort of thymo...

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Bibliografische gegevens
Hoofdauteurs: Dzhagalov, Ivan Lilyanov, Chen, Katherine Grace, Herzmark, Paul, Robey, Ellen A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660248/
https://ncbi.nlm.nih.gov/pubmed/23700386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001566
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