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Single-Molecule Threshold of HIV Fate Decision
During early infection, the HIV virus makes a key decision between two states: lytic and lysogenic fate. Deterministic bistability requires combination of positive feedback and ultrasensitivity. Although HIV circuity includes positive feedback activation of the Tat transactivator, it lacks ultrasens...
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| Publicado no: | Biophys J |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474877/ https://ncbi.nlm.nih.gov/pubmed/28591597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.03.041 |
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