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Chimeric TALE recombinases with programmable DNA sequence specificity
Site-specific recombinases are powerful tools for genome engineering. Hyperactivated variants of the resolvase/invertase family of serine recombinases function without accessory factors, and thus can be re-targeted to sequences of interest by replacing native DNA-binding domains (DBDs) with engineer...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510496/ https://ncbi.nlm.nih.gov/pubmed/23019222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks875 |
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