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Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase
The development of new methods for gene addition to mammalian genomes is necessary to overcome the limitations of conventional genetic engineering strategies. Although a variety of DNA-modifying enzymes have been used to directly catalyze the integration of plasmid DNA into mammalian genomes, there...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177191/ https://ncbi.nlm.nih.gov/pubmed/21653554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr421 |
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