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A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells
Zinc-finger recombinases (ZFRs) represent a potentially powerful class of tools for targeted genetic engineering. These chimeric enzymes are composed of an activated catalytic domain derived from the resolvase/invertase family of serine recombinases and a custom-designed zinc-finger DNA-binding doma...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616721/ https://ncbi.nlm.nih.gov/pubmed/23393187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt071 |
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