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Structure-guided reprogramming of serine recombinase DNA sequence specificity
Routine manipulation of cellular genomes is contingent upon the development of proteins and enzymes with programmable DNA sequence specificity. Here we describe the structure-guided reprogramming of the DNA sequence specificity of the invertase Gin from bacteriophage Mu and Tn3 resolvase from Escher...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021078/ https://ncbi.nlm.nih.gov/pubmed/21187418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014214108 |
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