Llwytho...

Structure-guided reprogramming of serine recombinase DNA sequence specificity

Routine manipulation of cellular genomes is contingent upon the development of proteins and enzymes with programmable DNA sequence specificity. Here we describe the structure-guided reprogramming of the DNA sequence specificity of the invertase Gin from bacteriophage Mu and Tn3 resolvase from Escher...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gaj, Thomas, Mercer, Andrew C., Gersbach, Charles A., Gordley, Russell M., Barbas III, Carlos F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021078/
https://ncbi.nlm.nih.gov/pubmed/21187418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014214108
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