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IFN-γ limits Th9 mediated autoimmune inflammation through dendritic cell modulation of IL-27

IL-9 producing Th9 cells have been associated with autoimmune diseases, such as experimental autoimmune encephalitis. However, the factors that negatively regulate Th9 cells during autoimmune inflammation are unclear. Here we show that IFN-γ inhibits Th9 differentiation both in vitro and in vivo. Th...

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Bibliografske podrobnosti
Main Authors: Murugaiyan, Gopal, Beynon, Vanessa, da Cunha, Andre Pires, Joller, Nicole, Weiner, Howard L.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504131/
https://ncbi.nlm.nih.gov/pubmed/23125412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200808
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