1,3-BUTADIENE: BIOMARKERS AND APPLICATION TO RISK ASSESSMENT

1,3-Butadiene (BD) is a known rodent and human carcinogen that is metabolized mainly by P450 2E1 to three epoxides, 1,2-epoxy-3-butene (EB), 1,2:3,4-diepoxybutane (DEB) and 1,2-epoxy-3,4-butanediol (EB-diol). The individual epoxides vary up to 200-fold in their mutagenic potency, with DEB being the...

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Xehetasun bibliografikoak
Egile Nagusiak: Swenberg, James A., Bordeerat, Narisa K., Boysen, Gunnar, Carro, Sujey, Georgieva, Nadia I., Nakamura, Jun, Troutman, John M., Upton, Patricia B., Albertini, Richard J., Vacek, Pamela M., Walker, Vernon E., Sram, Radim J., Goggin, Melissa, Tretyakova, Natalia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501005/
https://ncbi.nlm.nih.gov/pubmed/20974116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.10.010
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