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Persistence and Repair of Bifunctional DNA Adducts in Tissues of Laboratory Animals Exposed to 1,3-Butadiene by Inhalation

1,3-butadiene (BD) is an important industrial and environmental chemical classified as a human carcinogen. The mechanism of BD-mediated cancer is of significant interest because of the widespread exposure of humans to BD from cigarette smoke and urban air. BD is metabolically activated to 1,2,3,4-di...

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Библиографические подробности
Главные авторы: Goggin, Melissa, Sangaraju, Dewakar, Walker, Vernon E., Wickliffe, Jeffrey, Swenberg, James A., Tretyakova, Natalia
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118934/
https://ncbi.nlm.nih.gov/pubmed/21452897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200009b
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