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Column switching HPLC-ESI(+)-MS/MS methods for quantitative analysis of exocyclic dA adducts in DNA of laboratory animals exposed to 1,3-butadiene

1,3-butadiene (BD) is an important industrial and environmental chemical classified as a human carcinogen based on epidemiological evidence for an increased incidence of leukemia in workers occupationally exposed to BD and its potent carcinogenicity in laboratory rats and mice. BD is metabolically a...

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Bibliografische gegevens
Hoofdauteurs: Goggin, Melissa, Seneviratne, Uthpala, Swenberg, James A., Walker, Vernon E., Tretyakova, Natalia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878936/
https://ncbi.nlm.nih.gov/pubmed/20229982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900439w
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