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Quantitative HPLC-electrospray ionization-MS/MS analysis of the adenine-guanine cross-links of 1,2,3,4-diepoxybutane in tissues of butadiene-exposed B6C3F1 mice

1,3-Butadiene (BD) is an important industrial chemical used in the rubber and plastics manufacture, as well as an environmental pollutant present in automobile exhaust and cigarette smoke. It is classified as a known human carcinogen based on the epidemiological evidence in occupationally exposed wo...

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Bibliographische Detailangaben
Hauptverfasser: Goggin, Melissa, Anderson, Chris, Park, Soobong, Swenberg, James, Walker, Vernon, Tretyakova, Natalia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825381/
https://ncbi.nlm.nih.gov/pubmed/18442269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800051y
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