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Quantitative HPLC-electrospray ionization-MS/MS analysis of the adenine-guanine cross-links of 1,2,3,4-diepoxybutane in tissues of butadiene-exposed B6C3F1 mice

1,3-Butadiene (BD) is an important industrial chemical used in the rubber and plastics manufacture, as well as an environmental pollutant present in automobile exhaust and cigarette smoke. It is classified as a known human carcinogen based on the epidemiological evidence in occupationally exposed wo...

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Detalhes bibliográficos
Main Authors: Goggin, Melissa, Anderson, Chris, Park, Soobong, Swenberg, James, Walker, Vernon, Tretyakova, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825381/
https://ncbi.nlm.nih.gov/pubmed/18442269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800051y
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