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Capillary HPLC-Accurate Mass MS/MS Quantitation of N7-(2, 3, 4-trihydroxybut-1-yl)-guanine Adducts of 1,3-Butadiene in Human Leukocyte DNA

1,3-butadiene (BD) is a high volume industrial chemical commonly used in polymer and rubber production. It is also present in cigarette smoke, automobile exhaust, and urban air, leading to widespread exposure of human populations. Upon entering the body, BD is metabolized to electrophilic epoxides,...

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Main Authors: Sangaraju, Dewakar, Villalta, Peter, Goggin, Melissa, Agunsoye, Maria O., Campbell, Colin, Tretyakova, Natalia
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907265/
https://ncbi.nlm.nih.gov/pubmed/23937706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400213m
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