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Capillary HPLC-Accurate Mass MS/MS Quantitation of N7-(2, 3, 4-trihydroxybut-1-yl)-guanine Adducts of 1,3-Butadiene in Human Leukocyte DNA

1,3-butadiene (BD) is a high volume industrial chemical commonly used in polymer and rubber production. It is also present in cigarette smoke, automobile exhaust, and urban air, leading to widespread exposure of human populations. Upon entering the body, BD is metabolized to electrophilic epoxides,...

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Detalhes bibliográficos
Main Authors: Sangaraju, Dewakar, Villalta, Peter, Goggin, Melissa, Agunsoye, Maria O., Campbell, Colin, Tretyakova, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907265/
https://ncbi.nlm.nih.gov/pubmed/23937706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400213m
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