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Capillary HPLC-Accurate Mass MS/MS Quantitation of N7-(2, 3, 4-trihydroxybut-1-yl)-guanine Adducts of 1,3-Butadiene in Human Leukocyte DNA

1,3-butadiene (BD) is a high volume industrial chemical commonly used in polymer and rubber production. It is also present in cigarette smoke, automobile exhaust, and urban air, leading to widespread exposure of human populations. Upon entering the body, BD is metabolized to electrophilic epoxides,...

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Bibliografische gegevens
Hoofdauteurs: Sangaraju, Dewakar, Villalta, Peter, Goggin, Melissa, Agunsoye, Maria O., Campbell, Colin, Tretyakova, Natalia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907265/
https://ncbi.nlm.nih.gov/pubmed/23937706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400213m
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