Inhibition of Bupropion Metabolism by Selegiline: Mechanism-Based Inactivation of Human CYP2B6 and Characterization of Glutathione and Peptide Adducts

Gelijkaardige items

• Polymorphic Variants of Cytochrome P450 2B6 (CYP2B6.4–CYP2B6.9) Exhibit Altered Rates of Metabolism for Bupropion and Efavirenz: A Charge-Reversal Mutation in the K139E Variant (CYP2B6.8) Impairs Formation of a Functional Cytochrome P450-Reductase Complex
  door: Zhang, Haoming, et al.
  Gepubliceerd in: (2011)
• Anandamide Oxidation by Wild-Type and Polymorphically Expressed CYP2B6 and CYP2D6
  door: Sridar, Chitra, et al.
  Gepubliceerd in: (2011)
• The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir
  door: Lin, Hsia-lien, et al.
  Gepubliceerd in: (2013)
• A Quantitative High-Throughput 96-well plate Fluorescence Assay for Mechanism-Based Inactivators of Cytochromes P450 Exemplified using CYP2B6
  door: Kenaan, Cesar, et al.
  Gepubliceerd in: (2010)
• Roles of Residues F206 and V367 in Human CYP2B6: Effects of Mutations on Androgen Hydroxylation, Mechanism-Based Inactivation, and Reversible Inhibition
  door: Lin, Hsia-lien, et al.
  Gepubliceerd in: (2016)