Antisense 2′-Deoxy, 2′-Fluoroarabino Nucleic Acid (2′F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids

Gymnosis is the process of the delivery of antisense oligodeoxynucleotides to cells, in the absence of any carriers or conjugation, that produces sequence-specific gene silencing. While gymnosis was originally demonstrated using locked nucleic acid (LNA) gapmers, 2′-deoxy-2′fluoroarabino nucleic aci...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Souleimanian, Naira, Deleavey, Glen F, Soifer, Harris, Wang, Sijian, Tiemann, Katrin, Damha, Masad J, Stein, Cy A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499694/
https://ncbi.nlm.nih.gov/pubmed/23344235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.35
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky