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Selection of 2′-Deoxy-2′-Fluoroarabino Nucleic Acid (FANA) Aptamers That Bind HIV-1 Integrase with Picomolar Affinity
[Image: see text] Systematic Evolution of Ligands by Exponential Enrichment (SELEX) is the iterative process by which nucleic acids that can bind with high affinity and specificity (termed aptamers) to specific protein targets are selected. Using a SELEX protocol adapted for Xeno-Nucleic Acid (XNA)...
Enregistré dans:
| Publié dans: | ACS Chem Biol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2019
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7005942/ https://ncbi.nlm.nih.gov/pubmed/31560515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00237 |
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