Antisense 2′-Deoxy, 2′-Fluoroarabino Nucleic Acid (2′F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids

Gymnosis is the process of the delivery of antisense oligodeoxynucleotides to cells, in the absence of any carriers or conjugation, that produces sequence-specific gene silencing. While gymnosis was originally demonstrated using locked nucleic acid (LNA) gapmers, 2′-deoxy-2′fluoroarabino nucleic aci...

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Detaylı Bibliyografya
Asıl Yazarlar: Souleimanian, Naira, Deleavey, Glen F, Soifer, Harris, Wang, Sijian, Tiemann, Katrin, Damha, Masad J, Stein, Cy A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499694/
https://ncbi.nlm.nih.gov/pubmed/23344235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.35
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