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Improvements in siRNA properties mediated by 2′-deoxy-2′-fluoro-β-d-arabinonucleic acid (FANA)

RNA interference (RNAi) has emerged recently as an efficient mechanism for specific gene silencing. Short double-stranded small interfering RNAs (siRNAs) are now widely used for cellular or drug target validation; however, their use for silencing clinically relevant genes in a therapeutic setting re...

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Detalhes bibliográficos
Main Authors: Dowler, Thomas, Bergeron, Denis, Tedeschi, Anna-Lisa, Paquet, Luc, Ferrari, Nicolay, Damha, Masad J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409815/
https://ncbi.nlm.nih.gov/pubmed/16554553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl033
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