Structures of SHV-1 β-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugation

Lignende værker

• Rational design of a β-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 Å crystal structure of wt SHV-1 complex with a penam sulfone
  af: Padayatti, Pius S., et al.
  Udgivet: (2006)
• Penam Sulfones and β-Lactamase Inhibition: SA2-13 and the Importance of the C2 Side Chain Length and Composition
  af: Rodkey, Elizabeth A., et al.
  Udgivet: (2014)
• The importance of the trans-enamine intermediate as a β-lactamase inhibition strategy probed in inhibitor-resistant SHV β-lactamase variants
  af: Ke, Wei, et al.
  Udgivet: (2012)
• Crystal Structures of KPC-2 β-Lactamase in Complex with 3-Nitrophenyl Boronic Acid and the Penam Sulfone PSR-3-226
  af: Ke, Wei, et al.
  Udgivet: (2012)
• Detecting a Quasi-stable Imine Species on the Reaction Pathway of SHV-1 β-Lactamase and 6β-(Hydroxymethyl)penicillanic Acid Sulfone
  af: Che, Tao, et al.
  Udgivet: (2014)