In Silico Discovery of Androgen Receptor Antagonists with Activity in Castration Resistant Prostate Cancer

Previously available androgen receptor (AR) antagonists (bicalutamide, flutamide, and nilutamide) have limited activity against AR in prostate cancers that relapse after castration [castration resistant prostate cancer (CRPC)]. However, recent AR competitive antagonists such as MDV3100, generated th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shen, Howard C., Shanmugasundaram, Kumaran, Simon, Nicholas I., Cai, Changmeng, Wang, Hongyun, Chen, Sen, Balk, Steven P., Rigby, Alan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487628/
https://ncbi.nlm.nih.gov/pubmed/23023563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1222
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados