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Reactivation of Androgen Receptor Regulated TMPRSS2:ERG Gene Expression in Castration Resistant Prostate Cancer

It appears clear that androgen receptor (AR) regulated expression of the TMPRSS2:ERG fusion gene plays an early role in prostate cancer (PC) development or progression, but the extent to which TMPRSS2:ERG is downregulated in response to androgen deprivation therapy and whether AR reactivates TMPRSS2...

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Detalhes bibliográficos
Main Authors: Cai, Changmeng, Wang, Hongyun, Xu, Youyuan, Chen, Shaoyong, Balk, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859723/
https://ncbi.nlm.nih.gov/pubmed/19584279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0395
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