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ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

Fusion of the androgen receptor-regulated (AR-regulated) TMPRSS2 gene with ERG in prostate cancer (PCa) causes androgen-stimulated overexpression of ERG, an ETS transcription factor, but critical downstream effectors of ERG-mediating PCa development remain to be established. Expression of the SOX9 t...

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Autors principals: Cai, Changmeng, Wang, Hongyun, He, Housheng Hansen, Chen, Sen, He, Lingfeng, Ma, Fen, Mucci, Lorelei, Wang, Qianben, Fiore, Christopher, Sowalsky, Adam G., Loda, Massimo, Liu, X. Shirley, Brown, Myles, Balk, Steven P., Yuan, Xin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582143/
https://ncbi.nlm.nih.gov/pubmed/23426182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66666
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