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ANDROGEN RECEPTOR CAG REPEAT POLYMORPHISM AND RISK OF TMPRSS2:ERG POSITIVE PROSTATE CANCER

BACKGROUND: The androgen receptor (AR) is an essential gene in prostate cancer pathogenesis and progression. Genetic variation in AR exists, including a polymorphic CAG repeat sequence that is inversely associated with transcriptional activity. Experimental data suggest that heightened AR activity f...

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Detalhes bibliográficos
Main Authors: Yoo, Sun, Pettersson, Andreas, Jordahl, Kristina M., Lis, Rosina T., Lindstrom, Sara, Meisner, Allison, Nuttall, Elizabeth J., Stack, Edward C., Stampfer, Meir J., Kraft, Peter, Brown, Myles, Loda, Massimo, Giovannucci, Edward L., Kantoff, Philip W., Mucci, Lorelei A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184923/
https://ncbi.nlm.nih.gov/pubmed/24925673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-14-0020
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