Association of prostate cancer risk variants with TMPRSS2:ERG status: evidence for distinct molecular subtypes

BACKGROUND: Numerous genetic variants have been confirmed as prostate cancer risk factors. These variants may confer susceptibility to the development of specific molecular alterations during tumor initiation and progression. The TMPRSS2:ERG gene fusion occurs in roughly 50% of prostate cancers. Gen...

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Bibliografiske detaljer
Udgivet i:Cancer Epidemiol Biomarkers Prev
Main Authors: Penney, Kathryn L., Pettersson, Andreas, Shui, Irene M., Graff, Rebecca E., Kraft, Peter, Lis, Rosina T., Sesso, Howard D., Loda, Massimo, Mucci, Lorelei A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873420/
https://ncbi.nlm.nih.gov/pubmed/26941365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-15-1078
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