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The TMPRSS2:ERG Fusion and Response to Androgen Deprivation Therapy for Prostate Cancer

BACKGROUND: In the United States, half of men with prostate cancer harbor the androgen-regulated gene fusion TMPRSS2:ERG. We hypothesized that men with TMPRSS2:ERG positive tumors are more responsive to androgen deprivation therapy (ADT). METHODS: We studied a cohort of 239 men with prostate cancer...

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I publikationen:Prostate
Huvudupphovsmän: Graff, Rebecca E., Pettersson, Andreas, Lis, Rosina T., DuPre, Natalie, Jordahl, Kristina M., Nuttall, Elizabeth, Rider, Jennifer R., Fiorentino, Michelangelo, Sesso, Howard D., Kenfield, Stacey A., Loda, Massimo, Giovannucci, Edward L., Rosner, Bernard, Nguyen, Paul L., Sweeney, Christopher J., Mucci, Lorelei A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424159/
https://ncbi.nlm.nih.gov/pubmed/25728532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22973
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