The TMPRSS2:ERG Fusion and Response to Androgen Deprivation Therapy for Prostate Cancer

BACKGROUND: In the United States, half of men with prostate cancer harbor the androgen-regulated gene fusion TMPRSS2:ERG. We hypothesized that men with TMPRSS2:ERG positive tumors are more responsive to androgen deprivation therapy (ADT). METHODS: We studied a cohort of 239 men with prostate cancer...

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Veröffentlicht in:Prostate
Hauptverfasser: Graff, Rebecca E., Pettersson, Andreas, Lis, Rosina T., DuPre, Natalie, Jordahl, Kristina M., Nuttall, Elizabeth, Rider, Jennifer R., Fiorentino, Michelangelo, Sesso, Howard D., Kenfield, Stacey A., Loda, Massimo, Giovannucci, Edward L., Rosner, Bernard, Nguyen, Paul L., Sweeney, Christopher J., Mucci, Lorelei A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424159/
https://ncbi.nlm.nih.gov/pubmed/25728532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22973
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