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Rapid Induction of Androgen Receptor Splice Variants by Androgen Deprivation in Prostate Cancer

PURPOSE: Mechanisms mediating androgen receptor (AR) reactivation in prostate cancer (PCa) that progresses after castration (castration-resistant prostate cancer, CRPC) and subsequent treatment with abiraterone (CYP17A1 inhibitor that further suppresses androgen synthesis) remain unclear. EXPERIMENT...

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Detalhes bibliográficos
Main Authors: Yu, Ziyang, Chen, Sen, Sowalsky, Adam G., Voznesensky, Olga S., Mostaghel, Elahe A., Nelson, Peter S., Cai, Changmeng, Balk, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022291/
https://ncbi.nlm.nih.gov/pubmed/24449822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1863
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