ErbB2 Signaling Increases Androgen Receptor Expression in Abiraterone-Resistant Prostate Cancer

PURPOSE: ErbB2 signaling appears to be increased and may enhance AR activity in a subset of CRPC, but agents targeting ErbB2 have not been effective. This study was undertaken to assess ErbB2 activity in abiraterone-resistant prostate cancer (PCa), and determine whether it may contribute to androgen...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Gao, Shuai, Ye, Huihui, Gerrin, Sean, Wang, Hongyun, Sharma, Ankur, Chen, Sen, Patnaik, Akash, Sowalsky, Adam G., Voznesensky, Olga, Han, Wanting, Yu, Ziyang, Mostaghel, Elahe A., Nelson, Peter S., Taplin, Mary-Ellen, Balk, Steven P., Cai, Changmeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947432/
https://ncbi.nlm.nih.gov/pubmed/26936914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2309
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