Phosphorylation of Androgen Receptor Serine 81 is Associated with its Reactivation in Castration-Resistant Prostate Cancer

Phosphorylation of serine 81 (pS81) in the N-terminal transactivation domain of the androgen receptor (AR) has been linked to its transcriptional activation in prostate cancer (PCa) cell lines, but in vivo studies have been limited. Moreover, the role of pS81 in the reactivation of AR when tumors re...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Lett
Auteurs principaux: Russo, Joshua W., Liu, Xiaming, Ye, Huihui, Calagua, Carla, Chen, Sen, Voznesensky, Olga, Condulis, James, Ma, Fen, Taplin, Mary-Ellen, Einstein, David J., Balk, Steven P., Chen, Shaoyong
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186500/
https://ncbi.nlm.nih.gov/pubmed/30217568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.09.014
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