Phosphorylation of Androgen Receptor Serine 81 is Associated with its Reactivation in Castration-Resistant Prostate Cancer

Phosphorylation of serine 81 (pS81) in the N-terminal transactivation domain of the androgen receptor (AR) has been linked to its transcriptional activation in prostate cancer (PCa) cell lines, but in vivo studies have been limited. Moreover, the role of pS81 in the reactivation of AR when tumors re...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Russo, Joshua W., Liu, Xiaming, Ye, Huihui, Calagua, Carla, Chen, Sen, Voznesensky, Olga, Condulis, James, Ma, Fen, Taplin, Mary-Ellen, Einstein, David J., Balk, Steven P., Chen, Shaoyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186500/
https://ncbi.nlm.nih.gov/pubmed/30217568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.09.014
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