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Phosphorylation of Androgen Receptor Serine 81 is Associated with its Reactivation in Castration-Resistant Prostate Cancer

Phosphorylation of serine 81 (pS81) in the N-terminal transactivation domain of the androgen receptor (AR) has been linked to its transcriptional activation in prostate cancer (PCa) cell lines, but in vivo studies have been limited. Moreover, the role of pS81 in the reactivation of AR when tumors re...

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Podrobná bibliografie
Vydáno v:Cancer Lett
Hlavní autoři: Russo, Joshua W., Liu, Xiaming, Ye, Huihui, Calagua, Carla, Chen, Sen, Voznesensky, Olga, Condulis, James, Ma, Fen, Taplin, Mary-Ellen, Einstein, David J., Balk, Steven P., Chen, Shaoyong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186500/
https://ncbi.nlm.nih.gov/pubmed/30217568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.09.014
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