Phosphorylation of the androgen receptor at Ser81 is co‐sustained by CDK1 and CDK9 and leads to AR‐mediated transactivation in prostate cancer

Androgen receptor (AR) is the principal molecule in prostate cancer (PCa) etiology and therapy. AR re‐activation still remains a major challenge during treatment of castration‐resistant prostate cancer (CRPC) tumors that relapse after castration therapies. Recent reports have indicated the enrichmen...

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Bibliografske podrobnosti
izdano v:Mol Oncol
Main Authors: Gao, XinTao, Liang, Jiaqian, Wang, LiYang, Zhang, Zhaoyang, Yuan, Penghui, Wang, Jiaxin, Gao, Yanfei, Ma, Fen, Calagua, Carla, Ye, Huihui, Voznesensky, Olga, Wang, Shaogang, Wang, Tao, Liu, Jihong, Chen, Shaoyong, Liu, Xiaming
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253089/
https://ncbi.nlm.nih.gov/pubmed/33932081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12968
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