Phosphorylation of the androgen receptor at Ser81 is co‐sustained by CDK1 and CDK9 and leads to AR‐mediated transactivation in prostate cancer

Androgen receptor (AR) is the principal molecule in prostate cancer (PCa) etiology and therapy. AR re‐activation still remains a major challenge during treatment of castration‐resistant prostate cancer (CRPC) tumors that relapse after castration therapies. Recent reports have indicated the enrichmen...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Gao, XinTao, Liang, Jiaqian, Wang, LiYang, Zhang, Zhaoyang, Yuan, Penghui, Wang, Jiaxin, Gao, Yanfei, Ma, Fen, Calagua, Carla, Ye, Huihui, Voznesensky, Olga, Wang, Shaogang, Wang, Tao, Liu, Jihong, Chen, Shaoyong, Liu, Xiaming
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253089/
https://ncbi.nlm.nih.gov/pubmed/33932081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12968
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